产品货号：
Z26036
中文名称：
SART1抗体
英文名称：
Anti-SART1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SART1 Antibody |
| 指标别名 | Ara1;Hom s 1;HOMS1;hSART 1;hSnu66;SART 1;SART1;SART1259;SNRNP110;Snu66;SNU66 homolog |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,ICC/IF,FCM,ELISA |
| 基因名称 | SART1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SART1 recombinant protein (Position:K125-K800). |
| 计算分子量 | 90KD |
| 实际分子量 | 110KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | U4/U6.U5 tri-snRNP-associated protein 1 is a protein that in humans is encoded by the SART1 gene.This gene encodes two proteins,the SART1(800) protein expressed in the nucleus of the majority of proliferating cells,and the SART1(259) protein expressed in the cytosol of epithelial cancers.The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation;its full-length sequence is not published yet.The two encoded proteins are thought to be involved in the regulation of proliferation.Both proteins have tumor-rejection antigens.The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients.This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy.The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. |
| Uniprot ID | O43290 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | spliceosome associated factor 1,recruiter of U4/U6.U5 tri-snRNP |
| 蛋白名全称 | U4/U6.U5 tri-snRNP-associated protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunofluorescence (IF) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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